CasNxEXPLORING Life, reengineeredConnect
Concept visualization of a donor kidney supported in a perfusion chamber while gloved hands adjust the tubing

ORGAN ENGINEERING

Engineering donor organs.
Before transplant.

CasNx is developing CRISPR treatments that act on donor organs outside the body.

Explore our science Partner with us
01 / The science behind CasNx
01

THE PUBLISHED FOUNDATION

Built on discovery.

Scientific concept illustration of a CRISPR enzyme complex holding a nucleic-acid guide in its binding cleft
PUBLICATION2026

Nature Biotechnology

A new way to guide CRISPR toward RNA.

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Conceptual blue RNA ribbon folded into a stem-loop with violet base pairs
PUBLICATION2023

Nature Communications

Expanding the language of CRISPR.

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Scientific concept of a researcher adding a clear formulation to a perfusion circuit beside a closed preservation chamber
PUBLICATION2026

Nature Reviews Bioengineering

A roadmap for treating donor organs with CRISPR.

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IN THE MEDIA

Part of a
bigger conversation.

All coverage & appearances +
CasNx co-founder Santosh Rananaware speaking into a Cheddar microphone during the interview.
Cheddar

This Medical Tech Startup is Enhancing the Lifespan of Donated Organs

Watch the interview +
Rushi Shah and Piyush Jain with interviewer Elora Duong in the laboratory during the Tech Tuesday segment.
WCJB TV20

Tech Tuesday: CasNx

Watch on YouTube +
CRISPR editorial molecular illustration accompanying the linked report.
Tech Times

Gene Editing Could Rescue 28,000 Discarded Organs: CRISPR Roadmap Targets Perfusion Window

Read the coverage +
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BUILD WITH US

The next chapter
starts with a conversation.

FOR INVESTORS

Build the possibility.

Discuss the platform, development milestones, and the future of organ engineering.

FOR RESEARCH & TRANSPLANT PARTNERS

Advance the evidence.

Explore collaborations in organ perfusion, delivery, and translational research.