The science.
The people.
The conversation.In the media.

CRISPR Medicine News examines the CasNx founders’ proposal to use temporary RNA silencing during donor-organ perfusion. The report covers early kidney-biopsy results and explains the remaining challenges in delivery, manufacturing, safety assessment and whole-organ translation before the approach could enter clinical use.

Reporting on the founders’ published perspective and the opportunity to deliver CRISPR treatments during organ perfusion.

External coverage; the publisher’s article contains a founder-name error.

A broad overview of UF engineering research includes a substantial section on CasNx and its effort to remove viruses from donor organs before transplantation. It identifies the company’s founders, shows the team beside a perfusion pump and connects the work to collaboration between engineering and transplant medicine.

UF Innovate reports on research introducing engineered DNA guides for CRISPR-Cas12 and describes the potential manufacturing and stability advantages of that approach. The brief directly connects the work to CasNx’s plans to treat donor organs before transplant and identifies the company as an Accelerate client.

UF explains a DNA-guided CRISPR system developed in Piyush Jain’s laboratory, including its intended advantages for RNA targeting and diagnostics. The article names Santosh Rananaware among the co-first authors and discusses possible donor-organ applications. It presents early research and future uses rather than an approved treatment.

Platform research coverage featuring CasNx founders.

Piyush Jain pitches CasNx to Jackson Streeter in UF Innovate Ventures’ Real Elevator Pitches series.

CasNx is included for donor-organ treatment.

In a Tech Tuesday segment, host Elora Duong interviews CasNx co-founders Piyush Jain and Rushi Shah about using CRISPR during organ perfusion. They explain the infection risks facing transplant recipients and describe ongoing work to reduce viral loads in donor organs before transplantation.

Tech Tuesday · Produced with UF Innovate and SCAD Media.

CasNx joins the biotechnology cohort.

The Cade Prize announces fifteen finalists for its 2025 competition, including CasNx in the healthcare category. The company is recognized for its proposed use of CRISPR on donor organs before surgery. The announcement explains the final judging format and the prizes available to category winners.

This detailed company feature recounts how a conversation between neighboring researchers led to CasNx. It describes the founders’ organ-perfusion research, their diagnostic work and Nucleate Florida awards. The article makes clear that transplantation into patients remains a future goal requiring further development and regulatory approval.

UF Innovate announces Piyush Jain’s selection as a National Academy of Inventors Senior Member alongside UF colleague Nian Wang. The brief identifies Jain as a chemical-engineering professor and CasNx co-founder. Its focus is an individual inventor honor, rather than a company award or organ-treatment milestone.

Founder recognition: Piyush Jain.